Potential side effects of Crestor, a blockbuster cholesterol drug that
has been used by millions of people, may be linked to an increased the risk of
serious and potentially life-threatening heart problems, such as
cardiomyopathy, as well as Crestor diabetes. These risks, though, seem to be
heightened in the Asian population who have taken the drug. While the Crestor patients did have reduce levels of LDL
-”bad”- cholesterol and an inflammatory marker called C-reactive protein, as
well as reduced heart-related
Wednesday, October 26, 2011
Friday, October 21, 2011
Lawyers Looking At Crestor Risks, In Spite of Company’s Claims to Safety
Touted as a “super statin,” Crestor is
prescribed to treat high cholesterol and prevent cardivascular disease. The
U.S. Food and Drug and Administration (FDA) issued approval for the drug in
August 2003, and in the years since, there have been potentially fatal conditions linked as side effects of Crestor. According to recent research, the statin drug may increase the risk of heart problems, and lead to Crestor cardiomyopathy,
which is a disease that makes it difficult for the heart to pump blood
throughout the body. In some cases, this may result in the need for a heart
transplant. Crestor (atorvastatin) was approved by
the FDA in 2003 for the treatment of high cholesterol. It is a member of a
class of cholesterol-
Thursday, October 20, 2011
Crestor Surpasses Lipitor in Popularity With Physicians
Researchers
analyzing recent data about cholesterol-lowering drugs like Lipitor and
Crestor, known as statins, believe they have discovered a link between the
medications and an increased risk of diabetes. Despite this, for the past year, Crestor, a statin drug originally
approved to treat high cholesterol, has been increasingly used in people who
don’t have a cholesterol problem as a way to prevent heart attacks or strokes.
This expanded use was allowed despite growing concern about Crestor side effects, including liver damage, kidney damage, diabetes and a muscle pain and weakness. In severe cases, patients have developed a disease inflicted on the muscles called Crestor rhabdomyolysis. The U.S. Food & Drug Administration
Friday, October 14, 2011
Will Crestor Side Effects Be Suffered With Generic Crestor?
Watson Pharmaceuticals announced that its subsidiary, Watson
Laboratories, Inc., has received tentative approval from the United States Food
and Drug Administration for its rosuvastatin zinc 5, 10, 20 and 40 mg tablets.
Watson's rosuvastatin zinc tablets are a new salt form of AstraZeneca's Crestor
(rosuvastatin calcium) tablets. AstraZeneca filed suit against Watson on October
26, 2010 in the United States District Court for the District of Delaware
seeking to prevent Watson from commercializing its product prior to the
expiration of United States patent. AstraZeneca's lawsuit resulted in a stay of
final FDA approval of Watson's NDA until April 1, 2013 or until final
resolution of the matter before the court, whichever occurs sooner. In other legal matters Crestor lawsuits are being filed by patients who claimed serious, in some cases fatal side effects of Crestor. In terms of
the generic version, no studies have been published yet as to the risks
associated with rosuvastatin zinc like there have been with the brand-name
Crestor.
Wednesday, October 12, 2011
New Findings Point to Crestor Being More Dangerous Than Other Statins
For the past year, Crestor, a
statin drug originally approved to treat high cholesterol, has been
increasingly used in people who don’t have a cholesterol problem as a way to
prevent heart attacks or strokes. The U.S.
Food & Drug Administration (FDA)
approved the new Crestor indication regardless of the possibility of experiencing Crestor side effects, last February, after reviewing a clinical study
which showed a small reduction of strokes, heart attacks and other
“cardiovascular events” among people taking the statin, compared with patients
taking a placebo. The study was paid for by Astra Zeneca, the maker of Crestor.
It has recently been shown that high-dose use of
Crestor and other similar cholesterol drugs can increase the risk of developing diabetes, according to the findings of
a new study.
Studies have brought to light serious side effects of Crestor.
These include liver damage, kidney damage, diabetes and Crestor rhabdomyolysis. Critics
Wednesday, October 5, 2011
Crestor Side Effects: Patients Risk Lives for Health
Crestor lawsuits have been cropping up across the country
ever since reports have begun surfacing about the side effects that have been linked
to the statin drug. Statin drugs, which include the popular Lipitor and
Crestor, have proven effective in fighting cholesterol and associated medical
problems. Heart disease and strokes can be attributed in some cases to high
cholesterol, and studies have shown statin drugs to be extremely effective in
warding off heart problems after an initial stroke in certain patients, however there is potential for harmful Crestor side effects. It has
also been proven effective in patients with diabetes or metabolic syndrome,
conditions which under normal circumstances exacerbate the risk of heart
problems.
Tuesday, October 4, 2011
Crestor Pushes Hard To Cover Potential Risks
Crestor won FDA
approval in August 2003 in 5, 10, 20, and 40 mg. doses, but not the 80 mg.
dosage. In recent months there have been reports of serious side effects of Crestor use. Statins,
like Crestor, work by reducing production of cholesterol in the liver and by
increasing the ability of the liver to remove LDL (bad) cholesterol from the
blood. Statins reduce the level of LDL cholesterol in the blood and can reduce
triglyceride levels and increase levels of HDL (good) cholesterol.
As a result of
Crestor side effects, two major healthcare insurers with over 15 million
patients have refused to reimburse for Crestor. Still reeling from 31 cases of
fatal rhabdomyolysis caused by Baycol which was removed from the market in
2001, healthcare companies are taking a more cautious and conservative
approach. Other companies are placing Crestor in the highest tier of three
out-of-pocket categories to discourage Crestor prescriptions due to the risk of
Rhabdomyolysis. Crestor rhabdomyolysis causes
Crestor Side Effects Too Weighty to Risk?
Statins are the best-selling drugs in the
United States, with $14.5 billion in combined sales in 2008. They use the liver
to block the body’s creation of cholesterol, which is a key contributor to
coronary artery disease. Statin is used in a number of popular cholesterol
controlling drugs, including Crestor, Lipitor, Zocor, Mevacor, Lescol and
Pravachol. Within two months of Crestor hitting the shelves serious harmful and
dangerous side effects were brought to surface by those taking the drug. Not
long after taking the prescription drug some patients began suffering a number
of different harmful and dangerous side effects of Crestor.
Some other patients who had taken the
prescription drug Crestor began to suffer from acute kidney failure. This is a
condition that causes the kidney to fail, which is an instantly dangerous
condition. When this happens several steps need to initiated immediately to
avoid the risk of death. Some of these procedures include the removal of the
kidney, kidney dialysis therapy and more. Other patients who have used the
prescription drug reported Crestor cardiomyopothy, and
Monday, October 3, 2011
Study That Showed No Crestor Link To Heart Disease Now Accused of Being Subjective
Crestor has come under hot water as of late, due to issues concerning its effectiveness in treating cholesterol and its connection to kidney disease and Crestor congestive heart failure. The latest claims come as the drug industry struggles to clean up its image after a string of safety controversies that have sent its reputation to record lows. Public Citizen has been among the industry's most persistent critics, and recently turned its fire on Crestor, a cholesterol medicine from the UK's AstraZeneca which it claimed was unsafe. Now, on top of this, a study that claimed to show the reported benefits of Crestor’s ability to stave off heart disease, has been called into question.
The study has found that cholesterol medicines known as "statins", and Crestor in particular, may reduce the risk of strokes heart attacks and death by almost half when studied in patients with normal levels of cholesterol. Dr. Michel de Lergeril, however, of Joseph Fourier University in Grenoble, France, alleges that the JUPITER study “data set appears biased”. According to Dr. Lergeril, the JUPITER study had several inconsistencies in its research methods that, some have claimed, could be linked to fact that over half of the researchers involved had financial ties to AstraZeneca.
Statins are undeniably good at lowering cholesterol, and studies published early this year showed that they were also effective in reducing levels of a protein involved in inflammation, a separate risk factor in heart disease. This issue has arisen, however, of possible side effects that can be just as deadly as high cholesterol. In a research study conducted by the independent watchdog group, Public Citizen, prescription data for Crestor was compared to that of other statin drugs. This research study showed that Crestor caused rhabdomyolysis almost 22 times more than its lowest dose competitor and 3 times more than its highest dose competitor. If this happens the potential problems of higher cholesterol are then replaced with a very real and long lasting disease that may be worse than the original cholesterol problem.
The study has found that cholesterol medicines known as "statins", and Crestor in particular, may reduce the risk of strokes heart attacks and death by almost half when studied in patients with normal levels of cholesterol. Dr. Michel de Lergeril, however, of Joseph Fourier University in Grenoble, France, alleges that the JUPITER study “data set appears biased”. According to Dr. Lergeril, the JUPITER study had several inconsistencies in its research methods that, some have claimed, could be linked to fact that over half of the researchers involved had financial ties to AstraZeneca.
Statins are undeniably good at lowering cholesterol, and studies published early this year showed that they were also effective in reducing levels of a protein involved in inflammation, a separate risk factor in heart disease. This issue has arisen, however, of possible side effects that can be just as deadly as high cholesterol. In a research study conducted by the independent watchdog group, Public Citizen, prescription data for Crestor was compared to that of other statin drugs. This research study showed that Crestor caused rhabdomyolysis almost 22 times more than its lowest dose competitor and 3 times more than its highest dose competitor. If this happens the potential problems of higher cholesterol are then replaced with a very real and long lasting disease that may be worse than the original cholesterol problem.
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