High Rate of Side Effects Damage Crestor’s Reputation

Crestor was initially developed by the Japanese pharmaceutical company Shionogi and was in-licensed to Astra-Zeneca, an international pharmaceutical company, in April 1998. The FDA approved Crestor in August 2003. Multiple clinical studies have confirmed the effectiveness of Crestor side effects in reducing LDL-C ('bad' cholesterol) and raising HDL-C ('good' cholesterol). Crestor is now treating over 4.5 million patients worldwide.Crestor belongs to a family of drugs called Statins. Statins combat cholesterol by blocking a specific enzyme in the body that synthesizes cholesterol. All Statins are accompanied by a higher risk of a dangerous and potentially fatal condition called Crestor rhabdomyolysis, but Crestor is particularly closely associated with it.

Statins are among the best-selling drugs in the United States, with $14.5 billion in combined sales in 2008. They use the liver to block the body’s creation of cholesterol, which is a key contributor to coronary artery Crestor diabetes.The FDA recently issued a warning that 80mg Crestor doses increase the risk of rhabdomyolysis and other muscle injuries.

Crestor Side Effect Outline

Potential side effects of Crestor, a blockbuster cholesterol drug that has been used by millions of people, may be linked to an increased the risk of serious and potentially life-threatening Crestor heart problems, such as Crestor cardiomyopathy, as well as diabetes. Crestor (atorvastatin) was approved by the FDA in 2003 for the treatment of high cholesterol. It is a member of a class of cholesterol-lowering drugs known as statins. The drug is a direct competitor for Pfizer’s Lipitor and has a 12% market share of the $21 billion U.S. statin industry.

For the past year, Crestor, a statin drug originally approved to treat high cholesterol, has been increasingly used in people who don’t have a cholesterol problem as a way to prevent heart attacks or strokes. This expanded use was allowed despite growing concern about Crestor side effects, including liver damage, kidney damage, diabetes and a muscle disease called rhabdomyolysis.

Crestor Lawsuits Seek Number of Damages

Crestor side effects have driven many patients of the cholesterol-reducing statin drug to file suit against drugmaker AstraZeneca in order to gain damages that could compensate for their serious injuries and diseases from the drug. Most of the lawsuits allege that AstraZeneca was aware of the serious side effects, such as muscle injury, type 2 diabetes milletus, congestive heart failure, necrotic pancreatitis, and Crestor rhabdomyolysis, and should have warned the public about them. If the drugmaker was not, in fact, aware of these Crestor side effects, some lawsuits continue, they should have been—and may have been negligent in clinical trials.

The Food and Drug Administration issued a warning about “serious muscle toxicity” associated with Crestor and other statin drugs such as Zocor and Lipitor in 2005, after many patients had already sought legal aid in their battle against the drugmaker. Statins are now gaining a reputation, notorious for causing muscle damage, Crestor heart problems and other serious complications to patients who are only seeking to lower their cholesterol.

Asian Population at Highest Risk of Crestor Side Effects

Potential side effects of Crestor, a blockbuster cholesterol drug that has been used by millions of people, may be linked to an increased the risk of serious and potentially life-threatening heart problems, such as cardiomyopathy, as well as Crestor diabetes. These risks, though, seem to be heightened in the Asian population who have taken the drug. While the Crestor patients did have reduce levels of LDL -”bad”- cholesterol and an inflammatory marker called C-reactive protein, as well as reduced heart-related

Lawyers Looking At Crestor Risks, In Spite of Company’s Claims to Safety

Touted as a “super statin,” Crestor is prescribed to treat high cholesterol and prevent cardivascular disease. The U.S. Food and Drug and Administration (FDA) issued approval for the drug in August 2003, and in the years since, there have been potentially fatal conditions linked as side effects of Crestor. According to recent research, the statin drug may increase the risk of heart problems, and lead to Crestor cardiomyopathy, which is a disease that makes it difficult for the heart to pump blood throughout the body. In some cases, this may result in the need for a heart transplant. Crestor (atorvastatin) was approved by the FDA in 2003 for the treatment of high cholesterol. It is a member of a class of cholesterol-

Crestor Surpasses Lipitor in Popularity With Physicians

Researchers analyzing recent data about cholesterol-lowering drugs like Lipitor and Crestor, known as statins, believe they have discovered a link between the medications and an increased risk of diabetes. Despite this, for the past year, Crestor, a statin drug originally approved to treat high cholesterol, has been increasingly used in people who don’t have a cholesterol problem as a way to prevent heart attacks or strokes. This expanded use was allowed despite growing concern about Crestor side effects, including liver damage, kidney damage, diabetes and a muscle pain and weakness. In severe cases, patients have developed a disease inflicted on the muscles called Crestor rhabdomyolysis. The U.S. Food & Drug Administration

Will Crestor Side Effects Be Suffered With Generic Crestor?

Watson Pharmaceuticals announced that its subsidiary, Watson Laboratories, Inc., has received tentative approval from the United States Food and Drug Administration for its rosuvastatin zinc 5, 10, 20 and 40 mg tablets. Watson's rosuvastatin zinc tablets are a new salt form of AstraZeneca's Crestor (rosuvastatin calcium) tablets. AstraZeneca filed suit against Watson on October 26, 2010 in the United States District Court for the District of Delaware seeking to prevent Watson from commercializing its product prior to the expiration of United States patent. AstraZeneca's lawsuit resulted in a stay of final FDA approval of Watson's NDA until April 1, 2013 or until final resolution of the matter before the court, whichever occurs sooner. In other legal matters Crestor lawsuits are being filed by patients who claimed serious, in some cases fatal side effects of Crestor. In terms of the generic version, no studies have been published yet as to the risks associated with rosuvastatin zinc like there have been with the brand-name Crestor.